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05/28/2008
Lack of insulin, excess water passage
Insulin causes an increase of vasopressin, which explains why lack of insulin may lead not just to diabetes mellitus (characterized by hyperglycemia), but also to the lesser known diabetes insipidus (characterized by polyuria). Because of this, food intake will also decrease urine passage, which is why polyuria may also occur in anorexia nervosa.
The hypoglycemia caused by lack of insulin also causes a decrease of osmotic pressure in the blood plasma (glucose absorbs water). This may be responsible for the hyperhidrosis (excessive sweating) which is characteristic of hypoglycemia.
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